Participate in an online research study

Help Us get ON with Headache Research: Enrollment Now Closed

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Who Qualifies

Do you have frequent migraines or tension-type headaches?

If you fit in one of these groups, you may be interested in participating in a high-tech, online study exploring the connection between headaches and physiological data collected from a wrist-worn device.

Migraine Headache

migraine headacheMigraine headaches are a recurring type of headache. They cause moderate to severe pain, that is described as throbbing or pulsing, often on one side of the head. Nausea, weakness, and sensitivity to light and sound can also accompany migraine headaches.

Enrollment Goal:

250 people with frequent migraine headaches

221 Enrolled in Study

Tension-Type Headache

tension headacheTension-type headaches are the most common type of headache. Tension-type headaches involve discomfort in the head, scalp, or neck and are often associated with muscle tightness in these areas. Nausea, weakness, and sensitivity to light and sound do not accompany tension-type headaches.

Enrollment Goal:

50 people with frequent tension-type headaches

37 Enrolled in Study

Compensation

You will receive up to $240 in Visa or Mastercard giftcards for your participation in the study. The longer you participate in the study, up to 90 days total, the more money you’ll receive.

To receive the entire $240, you will need to:

  • Enroll in the study
  • Complete all 3 monthly surveys
  • Complete more than 79% of the daily questionnaires
  • Wear the charged Embrace2 device more than 68% of the time
  • Return the Embrace2

To find out more about compensation, please see the Frequently Asked Questions section.

Why Participate

In addition to receiving up to $240 in Visa or Mastercard giftcards, you’ll get to be a part of a high-tech, online study. In the study, you’ll wear the state-of-the-art Embrace2 sensor, which automatically tracks things like your steps, sleep activity, and skin temperature. This data is then sent to a smartphone app. This information may provide you with insight into your body and maybe even your headaches. Your participation will give researchers a better understanding of migraine and tension-type headaches, possibly leading to new treatments in the future.

get paid

Get Paid

Receive up to $240 in Visa or Mastercard giftcards.

use technology

Use Technology

Wear a state-of-the-art device and track your physiological data.

advance treatment

Advance Treatment

Help headache research move forward.

How It Works

Overall, you can expect to spend about 18 hours, spread over 3 months, doing things for this study. During this time, you’ll wear the Embrace2, a wrist-worn device, and complete questionnaires and surveys on the ProofPilot website using your smartphone or computer.

Qualify for the Study

How Long:

About 20 minutes

If you’re interested in participating in this study, click I’m Interested to get started. You will be taken to a page where you will agree to proceed to ProofPilot, the website we are using to conduct this study.

The next steps take place on the ProofPilot website. First, you’ll complete registration and answer questions about yourself. If you qualify for the study, you’ll read an informed consent document, which will tell you everything you need to know about participation. If you choose to participate, you’ll sign the informed consent document by reentering your password. Next, you’ll enter your name and mailing address so that we can ship your study Welcome Kit.

Enroll in Study

How Long:

About 1 hour

You will receive a Welcome Kit which includes your Embrace2 device in the mail within a week of ordering your kit. To set up your device you will need to:

  • Download the Empatica Mate App (Mate), which is the companion mobile app for your Embrace2 device
  • Open the Mate app and sign in with the account information provided to you
  • Charge the Embrace2 device
  • Pair the Embrace2 device with your smartphone

Once the study staff has confirmed that your Embrace2 is set up with the Mate app, you will be enrolled in the study.

You will be provided with a toll-free customer support phone number should you need help with your Embrace2 device or have any questions about the study.

Complete Daily Activities

How Long:

About 10 minutes

Each day of the study you will:

  • Wear the Embrace2 for at least 20 hours including at night
  • Charge the Embrace2 for at least 30 minutes
  • Stay within Bluetooth range of the Mate app on your smartphone as often as possible
  • Log your menstrual cycle start and end dates if applicable
  • Complete daily questionnaires on the ProofPilot website

The questionnaires on the ProofPilot website will ask you for information about whether or not you have a headache, the start and end times of your headache (if you have one), headache characteristics, medication use, mood and stress levels, how you feel and other things. The questionnaires can be completed using a web browser on any internet-connected device.

Complete Monthly Activities

How Long:

About 15 minutes

You will complete 3 monthly surveys, 1 per month, on the ProofPilot website. Each survey will ask you questions about your lifestyle, headaches and medication usage, and your quality of life.

Return Device

How Long:

About 10 minutes

You will receive a Return Kit as you are completing your final activities in the study. The Return Kit will have instructions for returning the Embrace2, as well as packaging and a pre-paid return label. You will need to return your device to receive your final compensation for the study.

Get Paid

How Long:

About 10 minutes

You will receive two electronic Visa or Mastercard giftcards worth up to $240 as compensation. Your first giftcard for $50 will be available within 72 hours of completing your enrollment by setting up your Embrace2 device. Your second giftcard for up to $190 will be available when you complete the study and return the Embrace2 device.

To redeem each giftcard, you will go to the ProofPilot website, open the Reward task, and click the Redeem Now button. When a Reward task becomes available for redemption, the ProofPilot website will send you a notification by email, SMS, or push notification. Upon redeeming a giftcard in ProofPilot, you will get an email with your giftcard and additional instructions to activate your card.

For more information about compensation, please see the section.

Frequently Asked Questions

If you decide to participate, your privacy will be carefully protected. All of the data collected from the study participants will be kept confidential and only de-identified data will be used to analyze study results. The results of the study, including your information, may also be presented in meetings at or in articles written about the study. If the results of the study are published, your identity will remain confidential.

For more information about privacy, please see our website privacy statement. You will also be provided with additional information about privacy when you read the informed consent document, which will be provided to you before you agree to participate in the study. The informed consent document will tell you everything you need to know about the study, and you will sign it before participating.

The main goal of this study is to use physiological data collected by the Embrace2 device to determine whether someone experienced a migraine headache on a specific day. Researchers are hoping to better understand the relationship between physiological data, and migraine and tension-type headaches.

We expect 300 people to take part in the study.

  • 250 people who experience frequent migraine headaches
  • 50 people who experience frequent tension-type headaches

The Embrace2 device is a prescription only, wrist-worn biosensor that automatically collects information about your physical activity, motion, skin temperature, and other things. The Embrace2 device uses Bluetooth to send the collected data to the Mate app. From here, the information is sent from the Mate app to Empatica’s cloud where it can be analyzed by researchers.

The Embrace2 wearable device will collect:

  • Physical activity (steps, movement intensity, rest)
  • Sleep duration and awake time
  • Skin temperature
  • Electrodermal Activity, which refers to electrical changes measured on the surface of the skin, that happen when the skin receives nerve signals from the brain

The questionnaires and surveys on the ProofPilot website will collect information about:

  • Demographic information like gender, education level, etc.
  • Medical history including other diseases or conditions
  • Migraine and tension-type headache history and characteristics
  • Current medications you are taking
  • Quality of life
  • Lifestyle information including diet, exercise frequency, sleep habits, etc.
  • Overall experience with the study
  • Mood and stress levels
  • How you are feeling overall
  • Headache information including
    • Presence of headaches
    • Start and end time
    • Type
    • Severity
    • Characteristics
    • Relief medication dosage
  • Location data
  • Zip code-based weather and air data

ProofPilot is the website that we are using to conduct this study. It can be accessed using your smartphone or computer. ProofPilot allows our researchers to communicate with, send reminders to, and collect data from study participants. If you choose to participate in this study, you will use the ProofPilot website to engage in a variety of study-related activities, like:

  • Answering questions to see if you qualify
  • Reading and signing the informed consent document, which describes the study in detail before you participate
  • Completing daily questionnaires and monthly surveys
  • Getting paid for your participation
  • Receiving reminders and notifications for study tasks and compensation

You will be provided a phone number for the Study Support Center if you need help related to your study participation. As always, if you have a medical emergency you will need to dial 911. Study staff cannot provide any immediate medical assistance.

The Embrace2 device will be provided to you at no cost. However, ProofPilot and the Empatica Mate App (Mate) may use your smartphone’s data plan. You will be responsible for any data charges. However, all study-related data can be transmitted using Wi-Fi. You can decide to use the apps only on Wi-Fi by managing the apps’ settings. This will prevent the apps from using data from your data plan.

You will receive up to $240 for completing study activities. The total amount you receive will depend on the study activities you complete. You will only be paid for the study activities you complete, and you must return your Embrace2 device to get your final compensation. Refer to the table below to see how much you will be paid for each study activity.

Your payment will be in the form of two Visa or Mastercard giftcards. The first giftcard for $50 will be available when you complete enrollment by setting up your Embrace2 device. The second giftcard for up to $190 will be available when you complete the study and return the Embrace2 device.

Study Compensation
Enrolling + Device + App Setup
Enrolling in the study and successfully setting up the Embrace2 with the Mate app. $50
Monthly Surveys
30 Days 60 Days 90 Days Maximum
$10 $10 $10 $30
Daily Surveys
10-40 41-70 71-90 Maximum
$25 $50 $100 $100
Wearing Charged Embrace2
15-30 31-60 61-90 Maximum
$20 $40 $60 $60
Study Maximum $240

To redeem each Visa or Mastercard giftcard, you will go to the ProofPilot website, open the Reward task, and click the Redeem Now button. When a Reward task becomes available for redemption, the ProofPilot website will send you a notification. The notification will be sent over email, text message, or push notification to your phone, or computer, depending on your communication preferences.

Upon redeeming a giftcard in ProofPilot, you will be taken to a giftcard provider to collect it. You’ll provide your name, address, phone number, and email to the giftcard provider for card activation. The giftcard provider will email you with a link and activation code. Click the link and enter your activation code to receive a giftcard number. You’ll need to write down this number to use your giftcard.

The giftcards are virtual cards. This means you’ll have a card number, expiration date, and security code, but no physical card. You can use your virtual card anywhere on the internet where credit cards are accepted. You can order a physical card if you’d like, but you’ll need to pay a fee to do so.

Your participation in this study is completely voluntary and you may stop participating at any time, without a penalty or loss of benefits to which you are otherwise entitled. You do not have to give a reason for leaving.

Your participation may also be stopped by the study researchers, ProofPilot study staff, or sponsors at any time for any reason.

If you have questions or would like to speak with someone before deciding if the study is a good fit for you, please call the Study Support Center at 855-675-7204.

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